The extracellular domains of FasL and Fas are sufficient for the formation of supramolecular FasL-Fas clusters of high stability. [electronic resource]
- The Journal of cell biology Mar 2005
- 1087-98 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9525
10.1083/jcb.200501048 doi
Adaptor Proteins, Signal Transducing--genetics Apoptosis--physiology Caspase 8 Caspases--genetics Cytoplasm--metabolism Extracellular Space--metabolism Fas Ligand Protein Fas-Associated Death Domain Protein HeLa Cells Humans Macromolecular Substances--metabolism Membrane Glycoproteins--chemistry Membrane Microdomains--metabolism Mutation--physiology Protein Binding--physiology Protein Structure, Tertiary--physiology Signal Transduction--drug effects Solubility--drug effects beta-Cyclodextrins--pharmacology fas Receptor--chemistry