Cytochrome P450 2C9 (CYP2C9) and vitamin K epoxide reductase (VKORC1) genotypes as determinants of acenocoumarol sensitivity. [electronic resource]
- Blood Jul 2005
- 135-40 p. digital
Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't
0006-4971
10.1182/blood-2005-01-0341 doi
Acenocoumarol--administration & dosage Administration, Oral Adolescent Adult Aged Anticoagulants--administration & dosage Aryl Hydrocarbon Hydroxylases--genetics Carcinoma, Hepatocellular Cell Line, Tumor Cytochrome P-450 CYP2C9 Drug Resistance--genetics Female Gene Frequency Genes, Reporter Haplotypes Humans Linear Models Liver Neoplasms Luciferases--genetics Male Middle Aged Mixed Function Oxygenases--genetics Predictive Value of Tests Vitamin K Epoxide Reductases