High doses of transplanted CD34+ cells are associated with rapid T-cell engraftment and lessened risk of graft rejection, but not more graft-versus-host disease after nonmyeloablative conditioning and unrelated hematopoietic cell transplantation. [electronic resource]
- Leukemia May 2005
- 822-8 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S.
0887-6924
10.1038/sj.leu.2403718 doi
Adolescent Adult Aged Antigens, CD34--analysis Child Child, Preschool Disease Progression Disease-Free Survival Female Graft Rejection--prevention & control Graft Survival Graft vs Host Disease--prevention & control Hematologic Neoplasms--therapy Hematopoietic Stem Cell Transplantation--methods Humans Immunosuppressive Agents--therapeutic use Male Middle Aged Reproducibility of Results Risk Factors Survival Analysis T-Lymphocytes--drug effects Transplantation Chimera--immunology Transplantation Conditioning--methods