The tuberous sclerosis protein TSC2 is not required for the regulation of the mammalian target of rapamycin by amino acids and certain cellular stresses. [electronic resource]
- The Journal of biological chemistry May 2005
- 18717-27 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M414499200 doi
AMP-Activated Protein Kinases Adaptor Proteins, Signal Transducing Adenosine Triphosphate--chemistry Amino Acids--chemistry Animals Calcium-Calmodulin-Dependent Protein Kinases--metabolism Carrier Proteins--chemistry Cell Cycle Proteins Cell Line Cells, Cultured Cycloheximide--pharmacology Dose-Response Relationship, Drug Elongation Factor 2 Kinase Eukaryotic Initiation Factors Fibroblasts--metabolism Gene Expression Regulation Glucose--chemistry Guanine--chemistry Guanosine Diphosphate--chemistry Guanosine Triphosphate--chemistry Humans Hydrogen Peroxide--pharmacology Hydrolysis Immunoblotting Immunoprecipitation Mice Models, Biological Monomeric GTP-Binding Proteins--chemistry Multienzyme Complexes--metabolism Mutation Neuropeptides--chemistry Phosphoproteins--chemistry Phosphorylation Protein Kinases--metabolism Protein Serine-Threonine Kinases--metabolism Protein Structure, Tertiary Protein Synthesis Inhibitors--pharmacology Ras Homolog Enriched in Brain Protein Repressor Proteins--metabolism Ribosomal Protein S6--metabolism Signal Transduction Sorbitol--pharmacology TOR Serine-Threonine Kinases Time Factors Transgenes Tuberous Sclerosis Complex 2 Protein Tumor Suppressor Proteins--metabolism