Boswellic acid acetate induces apoptosis through caspase-mediated pathways in myeloid leukemia cells. [electronic resource]
- Molecular cancer therapeutics Mar 2005
- 381-8 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
1535-7163
10.1158/1535-7163.MCT-03-0266 doi
Amino Acid Chloromethyl Ketones--pharmacology Apoptosis Blotting, Northern Blotting, Western Caspase 3 Caspases--metabolism Cell Line, Tumor Cell Proliferation DNA Fragmentation HL-60 Cells Humans Hydrogen Peroxide--pharmacology Inhibitory Concentration 50 K562 Cells Leukemia, Myeloid--drug therapy Membrane Potentials Mitochondria--metabolism Models, Biological Models, Chemical Oligopeptides--pharmacology Protein Binding Proto-Oncogene Proteins c-bcl-2--metabolism RNA, Messenger--metabolism Receptors, TNF-Related Apoptosis-Inducing Ligand Receptors, Tumor Necrosis Factor--metabolism Triterpenes--pharmacology U937 Cells bcl-2-Associated X Protein bcl-X Protein