Ono, Ryoichi

Dimerization of MLL fusion proteins and FLT3 activation synergize to induce multiple-lineage leukemogenesis. [electronic resource] - The Journal of clinical investigation Apr 2005 - 919-29 p. digital

Publication Type: Journal Article; Research Support, Non-U.S. Gov't

0021-9738

10.1172/JCI22725 doi


Animals
Cell Transformation, Neoplastic
Cell Transplantation
Cells, Cultured
Cytoskeletal Proteins
DNA Damage
DNA-Binding Proteins--chemistry
Dimerization
Enzyme Activation
GTP-Binding Proteins--chemistry
Hematopoietic Stem Cells--cytology
Histone-Lysine N-Methyltransferase
Humans
Infant
Leukemia, Myeloid, Acute--metabolism
Liver--pathology
Mice
Mice, Inbred C57BL
Myeloid-Lymphoid Leukemia Protein
Oncogene Proteins, Fusion--chemistry
Protein Structure, Tertiary
Proto-Oncogene Proteins--metabolism
Proto-Oncogenes--genetics
Receptor Protein-Tyrosine Kinases--metabolism
Recombinant Fusion Proteins--chemistry
Septins
Spleen--pathology
Transcription Factors--chemistry
fms-Like Tyrosine Kinase 3