van Herpen, Carla M L

Intratumoral recombinant human interleukin-12 administration in head and neck squamous cell carcinoma patients modifies locoregional lymph node architecture and induces natural killer cell infiltration in the primary tumor. [electronic resource] - Clinical cancer research : an official journal of the American Association for Cancer Research Mar 2005 - 1899-909 p. digital

Publication Type: Clinical Trial; Journal Article; Research Support, Non-U.S. Gov't

1078-0432

10.1158/1078-0432.CCR-04-1524 doi


Adjuvants, Immunologic--administration & dosage
Adult
Aged
CD4-Positive T-Lymphocytes--immunology
CD56 Antigen--analysis
CD8-Positive T-Lymphocytes--immunology
Carcinoma, Squamous Cell--drug therapy
Female
Head and Neck Neoplasms--drug therapy
Humans
Interferon-gamma--biosynthesis
Interleukin-12--administration & dosage
Killer Cells, Natural--immunology
Lymph Nodes--anatomy & histology
Male
Middle Aged
RNA, Messenger--biosynthesis