Wayne Conlan, J

Aerosol-, but not intradermal-immunization with the live vaccine strain of Francisella tularensis protects mice against subsequent aerosol challenge with a highly virulent type A strain of the pathogen by an alphabeta T cell- and interferon gamma- dependent mechanism. [electronic resource] - Vaccine Mar 2005 - 2477-85 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S.

0264-410X

10.1016/j.vaccine.2004.10.034 doi


Administration, Inhalation
Animals
Bacterial Vaccines--administration & dosage
CD4-Positive T-Lymphocytes--immunology
CD8-Positive T-Lymphocytes--immunology
Cytokines--analysis
Disease Models, Animal
Female
Francisella tularensis--immunology
Injections, Intradermal
Interferon-gamma--immunology
Lung--immunology
Mice
Mice, Inbred BALB C
Mice, Inbred C3H
Tularemia--prevention & control
Vaccines, Attenuated--administration & dosage