TY - GEN AU - Simonaro,Calogera M AU - D'Angelo,Marina AU - Haskins,Mark E AU - Schuchman,Edward H TI - Joint and bone disease in mucopolysaccharidoses VI and VII: identification of new therapeutic targets and biomarkers using animal models SN - 0031-3998 PY - 2005///0728 KW - Animals KW - Antimetabolites KW - pharmacology KW - Apoptosis KW - Biomarkers KW - metabolism KW - Bone Diseases KW - complications KW - Bromodeoxyuridine KW - Cats KW - Cell Proliferation KW - Cells, Cultured KW - Chondrocytes KW - cytology KW - Cytokines KW - Disease Models, Animal KW - Dogs KW - Immunoassay KW - Immunohistochemistry KW - Inflammation KW - Joint Diseases KW - Matrix Metalloproteinase 2 KW - biosynthesis KW - Matrix Metalloproteinase 9 KW - Mucopolysaccharidosis VI KW - Mucopolysaccharidosis VII KW - Nitric Oxide KW - Osteonectin KW - Rats KW - Reverse Transcriptase Polymerase Chain Reaction KW - Tibia KW - Time Factors KW - Tissue Inhibitor of Metalloproteinase-1 KW - Transforming Growth Factor beta N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1203/01.PDR.0000156510.96253.5A ER -