Artificial zinc finger fusions targeting Sp1-binding sites and the trans-activator-responsive element potently repress transcription and replication of HIV-1. [electronic resource]
- The Journal of biological chemistry Jun 2005
- 21545-52 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M414136200 doi
Binding Sites Cell Line Cell-Free System Chloramphenicol O-Acetyltransferase--metabolism Cyclin T Cyclins--chemistry Gene Deletion Gene Products, tat--metabolism HIV HIV-1--metabolism HeLa Cells Humans Models, Biological Mutation Peptides--chemistry Plasmids--metabolism Polymerase Chain Reaction Promoter Regions, Genetic Protein Binding Protein Structure, Tertiary RNA Polymerase II--chemistry Recombinant Fusion Proteins--chemistry Sp1 Transcription Factor--metabolism Transcription, Genetic Transcriptional Activation Zinc--chemistry Zinc Fingers tat Gene Products, Human Immunodeficiency Virus