Acid sphingomyelinase is indispensable for UV light-induced Bax conformational change at the mitochondrial membrane. [electronic resource]
- The Journal of biological chemistry May 2005
- 20804-13 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M410869200 doi
Apoptosis Caspase 3 Caspase 8 Caspases--metabolism Cathepsin D--metabolism Cell Membrane--chemistry Cell-Free System Ceramides--pharmacology Cytochromes c--metabolism Fluorescent Antibody Technique Gene Expression Green Fluorescent Proteins--genetics HeLa Cells Humans Mitochondria--ultrastructure Niemann-Pick Diseases--enzymology Protein Conformation--drug effects Proto-Oncogene Proteins c-bcl-2--chemistry RNA, Small Interfering--pharmacology Signal Transduction Sphingomyelin Phosphodiesterase--deficiency Ultraviolet Rays bcl-2-Associated X Protein