TY - GEN AU - Butler,M AU - Hayes,C S AU - Chappell,A AU - Murray,S F AU - Yaksh,T L AU - Hua,X-Y TI - Spinal distribution and metabolism of 2'-O-(2-methoxyethyl)-modified oligonucleotides after intrathecal administration in rats SN - 0306-4522 PY - 2005///0606 KW - Animals KW - Dose-Response Relationship, Drug KW - Drug Administration Schedule KW - Ganglia, Spinal KW - anatomy & histology KW - Glial Fibrillary Acidic Protein KW - metabolism KW - Immunohistochemistry KW - methods KW - Injections, Spinal KW - Male KW - Oligonucleotides, Antisense KW - administration & dosage KW - Phosphopyruvate Hydratase KW - Protein Kinase C KW - genetics KW - Protein Kinase C-alpha KW - RNA, Messenger KW - biosynthesis KW - Rats KW - Rats, Sprague-Dawley KW - Reverse Transcriptase Polymerase Chain Reaction KW - Spinal Cord KW - Thionucleotides KW - Time Factors KW - Tissue Distribution N1 - Publication Type: Comparative Study; Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1016/j.neuroscience.2004.11.038 ER -