TY - GEN AU - Kaabeche,Karim AU - Guenou,Hind AU - Bouvard,Daniel AU - Didelot,Nadège AU - Listrat,Antoine AU - Marie,Pierre J TI - Cbl-mediated ubiquitination of alpha5 integrin subunit mediates fibronectin-dependent osteoblast detachment and apoptosis induced by FGFR2 activation SN - 0021-9533 PY - 2005///0915 KW - Acetylcysteine KW - analogs & derivatives KW - Acrocephalosyndactylia KW - metabolism KW - Apoptosis KW - Blotting, Western KW - Caspase 3 KW - Caspase 9 KW - Caspases KW - Cell Adhesion KW - Cysteine Proteinase Inhibitors KW - pharmacology KW - DNA Primers KW - chemistry KW - Dose-Response Relationship, Drug KW - Electrophoresis, Polyacrylamide Gel KW - Fibronectins KW - Glutamine KW - Humans KW - Immunohistochemistry KW - Immunoprecipitation KW - Integrin alpha5 KW - Microscopy, Fluorescence KW - Mutation KW - Osteoblasts KW - Phosphotyrosine KW - Plasmids KW - Proteasome Endopeptidase Complex KW - Proteasome Inhibitors KW - Protein Binding KW - Protein Structure, Tertiary KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-bcl-2 KW - Proto-Oncogene Proteins c-cbl KW - RNA, Messenger KW - Receptor Protein-Tyrosine Kinases KW - Receptor, Fibroblast Growth Factor, Type 2 KW - Receptors, Fibroblast Growth Factor KW - Reverse Transcriptase Polymerase Chain Reaction KW - Skull KW - embryology KW - Time Factors KW - Transfection KW - Ubiquitin KW - Ubiquitin-Protein Ligases KW - bcl-2-Associated X Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1242/jcs.01679 ER -