TY - GEN AU - Liu,Sijiu AU - Lu,Zhibing AU - Han,Yin AU - Melamud,Eugene AU - Dunaway-Mariano,Debra AU - Herzberg,Osnat TI - Crystal structures of 2-methylisocitrate lyase in complex with product and with isocitrate inhibitor provide insight into lyase substrate specificity, catalysis and evolution SN - 0006-2960 PY - 2005///0418 KW - Amino Acid Sequence KW - Carbon-Carbon Lyases KW - chemistry KW - Catalysis KW - Cloning, Molecular KW - Conserved Sequence KW - Crystallography, X-Ray KW - Escherichia coli KW - enzymology KW - Escherichia coli Proteins KW - Evolution, Molecular KW - Kinetics KW - Magnesium KW - metabolism KW - Models, Molecular KW - Molecular Sequence Data KW - Protein Binding KW - Protein Conformation KW - Protein Structure, Secondary KW - Recombinant Proteins KW - Salmonella typhimurium KW - Sequence Alignment KW - Sequence Homology, Amino Acid KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi0479712 ER -