TY - GEN AU - Oelschlaeger,Peter AU - Mayo,Stephen L AU - Pleiss,Juergen TI - Impact of remote mutations on metallo-beta-lactamase substrate specificity: implications for the evolution of antibiotic resistance SN - 0961-8368 PY - 2005///0628 KW - Biological Evolution KW - Drug Design KW - Drug Resistance, Bacterial KW - genetics KW - Escherichia coli KW - enzymology KW - Kinetics KW - Mutation KW - Substrate Specificity KW - beta-Lactamases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1110/ps.041093405 ER -