TY - GEN AU - Sarbassov,D D AU - Guertin,David A AU - Ali,Siraj M AU - Sabatini,David M TI - Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex SN - 1095-9203 PY - 2005///0302 KW - 3-Phosphoinositide-Dependent Protein Kinases KW - Adaptor Proteins, Signal Transducing KW - Animals KW - Carrier Proteins KW - metabolism KW - Cell Line KW - Cell Line, Tumor KW - Drosophila Proteins KW - Drosophila melanogaster KW - Enzyme Activation KW - Humans KW - Hydrophobic and Hydrophilic Interactions KW - Immunoprecipitation KW - Phosphatidylinositol 3-Kinases KW - Phosphorylation KW - Protein Kinases KW - Protein Serine-Threonine Kinases KW - Proteins KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-akt KW - RNA Interference KW - Rapamycin-Insensitive Companion of mTOR Protein KW - Regulatory-Associated Protein of mTOR KW - Serine KW - TOR Serine-Threonine Kinases N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1126/science.1106148 ER -