Katiyar, Santosh K <br/><br/>
Silymarin induces apoptosis primarily through a p53-dependent pathway involving Bcl-2/Bax, cytochrome c release, and caspase activation.  [electronic resource] 

 -  Molecular cancer therapeutics  Feb 2005 
 - 207-16 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S. 
<br/><br/><label>ISSN: </label>1535-7163 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Amino Acid Chloromethyl Ketones--pharmacology<br/>Animals<br/>Apoptosis<br/>Apoptotic Protease-Activating Factor 1<br/>Caspase 3<br/>Caspase Inhibitors<br/>Caspases--metabolism<br/>Cell Line<br/>Cysteine Proteinase Inhibitors--pharmacology<br/>Cytochromes c--metabolism<br/>Down-Regulation<br/>Fibroblasts--drug effects<br/>Keratinocytes--drug effects<br/>Mice<br/>Phosphorylation--drug effects<br/>Poly(ADP-ribose) Polymerases--metabolism<br/>Proteins--metabolism<br/>Proto-Oncogene Proteins c-bcl-2--metabolism<br/>Silybin<br/>Silymarin--pharmacology<br/>Tumor Suppressor Protein p53--genetics<br/>bcl-2-Associated X Protein