TY  - GEN
AU  - Klein,Laura E
AU  - Freeze,B Scott
AU  - Smith,Amos B
AU  - Horwitz,Susan Band
TI  - The microtubule stabilizing agent discodermolide is a potent inducer of accelerated cell senescence
SN  - 1551-4005
PY  - 2006///0505
KW  - Alkanes
KW  - pharmacology
KW  - Antineoplastic Agents
KW  - Antineoplastic Agents, Phytogenic
KW  - Bromodeoxyuridine
KW  - Carbamates
KW  - Cell Line, Tumor
KW  - Cellular Senescence
KW  - Flow Cytometry
KW  - Gene Expression Regulation
KW  - Humans
KW  - Hydrogen-Ion Concentration
KW  - Inhibitory Concentration 50
KW  - Lactones
KW  - Microtubules
KW  - chemistry
KW  - Mitogen-Activated Protein Kinase 1
KW  - metabolism
KW  - Mitogen-Activated Protein Kinase 3
KW  - Mitosis
KW  - Paclitaxel
KW  - Phenotype
KW  - Pyrones
KW  - Signal Transduction
KW  - Time Factors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.4161/cc.4.3.1550
ER  -