TY - GEN AU - Taha,Tarek A AU - Kitatani,Kazuyuki AU - Bielawski,Jacek AU - Cho,Wonhwa AU - Hannun,Yusuf A AU - Obeid,Lina M TI - Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism SN - 0021-9258 PY - 2005///0621 KW - Apoptosis KW - Caspase 7 KW - Caspase 8 KW - Caspase Inhibitors KW - Caspases KW - metabolism KW - Cathepsin B KW - Cell Death KW - Cell Line, Tumor KW - Cysteine Endopeptidases KW - Cytosol KW - Dose-Response Relationship, Drug KW - Down-Regulation KW - Electrophoresis, Polyacrylamide Gel KW - Enzyme Activation KW - Enzyme Inhibitors KW - pharmacology KW - Humans KW - Immunoblotting KW - Lysosomes KW - chemistry KW - Mass Spectrometry KW - Microscopy, Fluorescence KW - Phosphotransferases (Alcohol Group Acceptor) KW - Protein Binding KW - RNA, Small Interfering KW - Recombinant Proteins KW - Time Factors KW - Transfection KW - Tumor Necrosis Factor-alpha N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M413744200 ER -