Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. [electronic resource]
- The Journal of biological chemistry Apr 2005
- 17196-202 p. digital
Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.
0021-9258
10.1074/jbc.M413744200 doi
Apoptosis Caspase 7 Caspase 8 Caspase Inhibitors Caspases--metabolism Cathepsin B--metabolism Cell Death Cell Line, Tumor Cysteine Endopeptidases--metabolism Cytosol--metabolism Dose-Response Relationship, Drug Down-Regulation Electrophoresis, Polyacrylamide Gel Enzyme Activation Enzyme Inhibitors--pharmacology Humans Immunoblotting Lysosomes--chemistry Mass Spectrometry Microscopy, Fluorescence Phosphotransferases (Alcohol Group Acceptor)--metabolism Protein Binding RNA, Small Interfering--metabolism Recombinant Proteins--chemistry Time Factors Transfection Tumor Necrosis Factor-alpha--metabolism