Taha, Tarek A

Tumor necrosis factor induces the loss of sphingosine kinase-1 by a cathepsin B-dependent mechanism. [electronic resource] - The Journal of biological chemistry Apr 2005 - 17196-202 p. digital

Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S.; Research Support, U.S. Gov't, P.H.S.

0021-9258

10.1074/jbc.M413744200 doi


Apoptosis
Caspase 7
Caspase 8
Caspase Inhibitors
Caspases--metabolism
Cathepsin B--metabolism
Cell Death
Cell Line, Tumor
Cysteine Endopeptidases--metabolism
Cytosol--metabolism
Dose-Response Relationship, Drug
Down-Regulation
Electrophoresis, Polyacrylamide Gel
Enzyme Activation
Enzyme Inhibitors--pharmacology
Humans
Immunoblotting
Lysosomes--chemistry
Mass Spectrometry
Microscopy, Fluorescence
Phosphotransferases (Alcohol Group Acceptor)--metabolism
Protein Binding
RNA, Small Interfering--metabolism
Recombinant Proteins--chemistry
Time Factors
Transfection
Tumor Necrosis Factor-alpha--metabolism