TY - GEN AU - Lebowitz,Peter F AU - Eng-Wong,Jennifer AU - Widemann,Brigitte C AU - Balis,Frank M AU - Jayaprakash,Nalini AU - Chow,Catherine AU - Clark,Geoff AU - Gantz,Susan B AU - Venzon,David AU - Zujewski,JoAnne TI - A phase I trial and pharmacokinetic study of tipifarnib, a farnesyltransferase inhibitor, and tamoxifen in metastatic breast cancer SN - 1078-0432 PY - 2005///0531 KW - Adult KW - Aged KW - Alkyl and Aryl Transferases KW - antagonists & inhibitors KW - Anemia KW - chemically induced KW - Antineoplastic Agents, Hormonal KW - administration & dosage KW - Antineoplastic Combined Chemotherapy Protocols KW - therapeutic use KW - Area Under Curve KW - Breast Neoplasms KW - drug therapy KW - Dose-Response Relationship, Drug KW - Exanthema KW - Farnesyltranstransferase KW - Fatigue KW - Female KW - Humans KW - Leukocytes, Mononuclear KW - drug effects KW - Male KW - Middle Aged KW - Neoplasm Metastasis KW - Quinolones KW - Tamoxifen KW - Treatment Outcome N1 - Publication Type: Clinical Trial; Clinical Trial, Phase I; Comparative Study; Journal Article ER -