TY  - GEN
AU  - Flatten,Karen
AU  - Dai,Nga T
AU  - Vroman,Benjamin T
AU  - Loegering,David
AU  - Erlichman,Charles
AU  - Karnitz,Larry M
AU  - Kaufmann,Scott H
TI  - The role of checkpoint kinase 1 in sensitivity to topoisomerase I poisons
SN  - 0021-9258
PY  - 2005///0621
KW  - Antineoplastic Agents, Phytogenic
KW  - metabolism
KW  - Ataxia Telangiectasia Mutated Proteins
KW  - Camptothecin
KW  - analogs & derivatives
KW  - Cell Cycle Proteins
KW  - genetics
KW  - Cell Line
KW  - Checkpoint Kinase 1
KW  - Checkpoint Kinase 2
KW  - DNA Topoisomerases, Type I
KW  - Gene Deletion
KW  - Genes, cdc
KW  - HSP90 Heat-Shock Proteins
KW  - antagonists & inhibitors
KW  - Humans
KW  - Neoplasms
KW  - drug therapy
KW  - Protein Kinases
KW  - Protein Serine-Threonine Kinases
KW  - RNA, Small Interfering
KW  - Topoisomerase I Inhibitors
N1  - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, U.S. Gov't, P.H.S
UR  - https://doi.org/10.1074/jbc.M411890200
ER  -