Hritz, I

Proton pump inhibitor co-therapy normalizes the increased cell turnover of the gastric mucosa both in NSAID and selective COX-2 users. [electronic resource] - International journal of immunopathology and pharmacology - 75-84 p. digital

Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't

0394-6320

10.1177/039463200501800109 doi


Adult
Anti-Inflammatory Agents, Non-Steroidal--adverse effects
Apoptosis--drug effects
Cell Count
Cell Proliferation--drug effects
Cyclooxygenase 2
Cyclooxygenase 2 Inhibitors
Cyclooxygenase Inhibitors--adverse effects
DNA Damage--drug effects
Double-Blind Method
Enzyme Inhibitors--therapeutic use
Female
Gastric Mucosa--pathology
Genes, erbB-1--genetics
Genes, p53--genetics
Humans
Immunohistochemistry
In Situ Nick-End Labeling
Male
Membrane Proteins
Middle Aged
Proliferating Cell Nuclear Antigen--metabolism
Prostaglandin-Endoperoxide Synthases--metabolism
Proton Pump Inhibitors
Stomach Ulcer--chemically induced