Hritz, I
Proton pump inhibitor co-therapy normalizes the increased cell turnover of the gastric mucosa both in NSAID and selective COX-2 users. [electronic resource]
- International journal of immunopathology and pharmacology
- 75-84 p. digital
Publication Type: Clinical Trial; Journal Article; Randomized Controlled Trial; Research Support, Non-U.S. Gov't
ISSN: 0394-6320
Standard No.: 10.1177/039463200501800109 doi
Subjects--Topical Terms: Adult Anti-Inflammatory Agents, Non-Steroidal--adverse effects Apoptosis--drug effects Cell Count Cell Proliferation--drug effects Cyclooxygenase 2 Cyclooxygenase 2 Inhibitors Cyclooxygenase Inhibitors--adverse effects DNA Damage--drug effects Double-Blind Method Enzyme Inhibitors--therapeutic use Female Gastric Mucosa--pathology Genes, erbB-1--genetics Genes, p53--genetics Humans Immunohistochemistry In Situ Nick-End Labeling Male Membrane Proteins Middle Aged Proliferating Cell Nuclear Antigen--metabolism Prostaglandin-Endoperoxide Synthases--metabolism Proton Pump Inhibitors Stomach Ulcer--chemically induced