TY - GEN AU - Kuster,Gabriela M AU - Kotlyar,Eugene AU - Rude,Mary K AU - Siwik,Deborah A AU - Liao,Ronglih AU - Colucci,Wilson S AU - Sam,Flora TI - Mineralocorticoid receptor inhibition ameliorates the transition to myocardial failure and decreases oxidative stress and inflammation in mice with chronic pressure overload SN - 1524-4539 PY - 2005///0711 KW - Animals KW - Aorta KW - Apoptosis KW - Blood Pressure KW - Cell Size KW - Chronic Disease KW - Constriction, Pathologic KW - complications KW - Drug Evaluation, Preclinical KW - Eplerenone KW - Fibrosis KW - Heart Failure KW - etiology KW - Hypertrophy, Left Ventricular KW - Intercellular Adhesion Molecule-1 KW - analysis KW - Ligation KW - Male KW - Matrix Metalloproteinases KW - Mice KW - Mineralocorticoid Receptor Antagonists KW - Myocarditis KW - drug therapy KW - Myocardium KW - chemistry KW - Myocytes, Cardiac KW - pathology KW - Oxidative Stress KW - drug effects KW - Pressure KW - Random Allocation KW - Receptors, Mineralocorticoid KW - physiology KW - Spironolactone KW - analogs & derivatives KW - Tissue Inhibitor of Metalloproteinase-1 KW - Tissue Inhibitor of Metalloproteinase-2 KW - Tyrosine N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1161/01.CIR.0000153800.09920.40 ER -