TY  - GEN
AU  - Trifilieff,Alexandre
AU  - Keller,Thomas H
AU  - Press,Neil J
AU  - Howe,Trevor
AU  - Gedeck,Peter
AU  - Beer,David
AU  - Walker,Christoph
TI  - CGH2466, a combined adenosine receptor antagonist, p38 mitogen-activated protein kinase and phosphodiesterase type 4 inhibitor with potent in vitro and in vivo anti-inflammatory activities
SN  - 0007-1188
PY  - 2005///0929
KW  - 3',5'-Cyclic-AMP Phosphodiesterases
KW  - antagonists & inhibitors
KW  - Animals
KW  - Anti-Inflammatory Agents, Non-Steroidal
KW  - chemistry
KW  - Cricetinae
KW  - Cyclic Nucleotide Phosphodiesterases, Type 3
KW  - Cyclic Nucleotide Phosphodiesterases, Type 4
KW  - Dose-Response Relationship, Drug
KW  - Female
KW  - Humans
KW  - Imidazoles
KW  - Mice
KW  - Mice, Inbred BALB C
KW  - Mice, Inbred C57BL
KW  - Phosphodiesterase Inhibitors
KW  - Protein Kinase Inhibitors
KW  - Purinergic P1 Receptor Antagonists
KW  - Pyridines
KW  - Receptors, Purinergic P1
KW  - metabolism
KW  - Thiazoles
KW  - p38 Mitogen-Activated Protein Kinases
N1  - Publication Type: Comparative Study; Journal Article
UR  - https://doi.org/10.1038/sj.bjp.0706132
ER  -