TY - GEN AU - Mure,Minae AU - Kurtis,Christian R AU - Brown,Doreen E AU - Rogers,Melanie S AU - Tambyrajah,Winston S AU - Saysell,Colin AU - Wilmot,Carrie M AU - Phillips,Simon E V AU - Knowles,Peter F AU - Dooley,David M AU - McPherson,Michael J TI - Active site rearrangement of the 2-hydrazinopyridine adduct in Escherichia coli amine oxidase to an azo copper(II) chelate form: a key role for tyrosine 369 in controlling the mobility of the TPQ-2HP adduct SN - 0006-2960 PY - 2005///0607 KW - Amine Oxidase (Copper-Containing) KW - antagonists & inhibitors KW - Asparagine KW - genetics KW - Aspartic Acid KW - Azo Compounds KW - chemistry KW - Binding Sites KW - Cations, Divalent KW - Chelating Agents KW - Cobalt KW - Copper KW - Crystallography, X-Ray KW - Enzyme Inhibitors KW - Enzyme Stability KW - Escherichia coli Proteins KW - Glutamic Acid KW - Hydrogen-Ion Concentration KW - Mutagenesis, Site-Directed KW - Phenylalanine KW - Pyridones KW - Resorcinols KW - Spectrometry, Mass, Electrospray Ionization KW - Spectrophotometry, Ultraviolet KW - Spectrum Analysis, Raman KW - Tyrosine N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi0479860 ER -