TY - GEN AU - Mure,Minae AU - Brown,Doreen E AU - Saysell,Colin AU - Rogers,Melanie S AU - Wilmot,Carrie M AU - Kurtis,Christian R AU - McPherson,Michael J AU - Phillips,Simon E V AU - Knowles,Peter F AU - Dooley,David M TI - Role of the interactions between the active site base and the substrate Schiff base in amine oxidase catalysis. Evidence from structural and spectroscopic studies of the 2-hydrazinopyridine adduct of Escherichia coli amine oxidase SN - 0006-2960 PY - 2005///0607 KW - Amine Oxidase (Copper-Containing) KW - antagonists & inhibitors KW - Binding Sites KW - genetics KW - Catalysis KW - Crystallography, X-Ray KW - Enzyme Inhibitors KW - chemistry KW - Enzyme Stability KW - Escherichia coli Proteins KW - Hydrogen-Ion Concentration KW - Kinetics KW - Mutagenesis, Site-Directed KW - Nuclear Magnetic Resonance, Biomolecular KW - Pyridones KW - Schiff Bases KW - metabolism KW - Solutions KW - Spectrophotometry, Ultraviolet KW - Spectrum Analysis, Raman KW - Substrate Specificity KW - Titrimetry N1 - Publication Type: Journal Article; Research Support, N.I.H., Extramural; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1021/bi047988k ER -