A simple rodent assay for the in vivo identification of agents with potential to reduce levodopa-induced dyskinesia in Parkinson's disease. [electronic resource]
- Experimental neurology Feb 2005
- 243-50 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0014-4886
10.1016/j.expneurol.2004.10.002 doi
Adrenergic Uptake Inhibitors--pharmacology Adrenergic alpha-Antagonists--therapeutic use Amantadine--therapeutic use Animals Anti-Dyskinesia Agents--therapeutic use Antiparkinson Agents--adverse effects Dizocilpine Maleate--therapeutic use Dopamine Agents--therapeutic use Dose-Response Relationship, Drug Drug Evaluation, Preclinical--methods Dyskinesia, Drug-Induced--drug therapy Excitatory Amino Acid Antagonists--therapeutic use Haloperidol--therapeutic use Idazoxan--therapeutic use Levodopa--adverse effects Male Motor Activity--drug effects Parkinson Disease--drug therapy Rats Rats, Sprague-Dawley Reserpine--pharmacology