TY - GEN AU - Liu,Wanli AU - Chen,Ying-Hua TI - High epitope density in a single protein molecule significantly enhances antigenicity as well as immunogenicity: a novel strategy for modern vaccine development and a preliminary investigation about B cell discrimination of monomeric proteins SN - 0014-2980 PY - 2005///0329 KW - Animals KW - Antibodies, Monoclonal KW - immunology KW - Antigens KW - B-Lymphocytes KW - Enzyme-Linked Immunosorbent Assay KW - Epitopes KW - Glutathione Transferase KW - genetics KW - Kinetics KW - Orthomyxoviridae KW - Protein Binding KW - Proteins KW - Rabbits KW - Recombinant Fusion Proteins KW - Surface Plasmon Resonance KW - Time Factors KW - Vaccines N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1002/eji.200425749 ER -