Aichberger, Karl J <br/><br/>
Identification of mcl-1 as a BCR/ABL-dependent target in chronic myeloid leukemia (CML): evidence for cooperative antileukemic effects of imatinib and mcl-1 antisense oligonucleotides.  [electronic resource] 

 -  Blood  Apr 2005 
 - 3303-11 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-4971 
<br/><br/><label>Standard No.: </label>10.1182/blood-2004-02-0749  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antineoplastic Agents--pharmacology<br/>Benzamides<br/>Cell Survival--physiology<br/>DNA-Binding Proteins--metabolism<br/>Down-Regulation<br/>Extracellular Signal-Regulated MAP Kinases--metabolism<br/>Fusion Proteins, bcr-abl--genetics<br/>Gene Expression Regulation, Leukemic--drug effects<br/>Humans<br/>Imatinib Mesylate<br/>In Vitro Techniques<br/>K562 Cells<br/>Leukemia, Myelogenous, Chronic, BCR-ABL Positive--drug therapy<br/>MAP Kinase Kinase Kinases--metabolism<br/>Milk Proteins--metabolism<br/>Myeloid Cell Leukemia Sequence 1 Protein<br/>Neoplasm Proteins--genetics<br/>Oligonucleotides, Antisense--pharmacology<br/>Piperazines--pharmacology<br/>Proto-Oncogene Proteins c-bcl-2--genetics<br/>Pyrimidines--pharmacology<br/>RNA, Small Interfering--pharmacology<br/>STAT5 Transcription Factor<br/>Trans-Activators--metabolism<br/>Tumor Cells, Cultured<br/>raf Kinases--metabolism<br/>ras Proteins--metabolism