TY - GEN AU - Covaceuszach,Sonia AU - Cattaneo,Antonino AU - Lamba,Doriano TI - Neutralization of NGF-TrkA receptor interaction by the novel antagonistic anti-TrkA monoclonal antibody MNAC13: a structural insight SN - 1097-0134 PY - 2006///0522 KW - Amino Acid Sequence KW - Animals KW - Antibodies, Monoclonal KW - chemistry KW - Binding Sites KW - Binding Sites, Antibody KW - Biochemical Phenomena KW - Biochemistry KW - Cloning, Molecular KW - Computational Biology KW - Crystallography, X-Ray KW - Enzyme-Linked Immunosorbent Assay KW - Epitope Mapping KW - Epitopes KW - Escherichia coli KW - metabolism KW - Gene Deletion KW - Immunoglobulin Fab Fragments KW - Kinetics KW - Mice KW - Models, Molecular KW - Molecular Conformation KW - Molecular Sequence Data KW - Mutation KW - Nerve Growth Factor KW - Peptide Library KW - Protein Binding KW - Protein Conformation KW - Protein Structure, Secondary KW - Protein Structure, Tertiary KW - Proteins KW - Receptor, Nerve Growth Factor KW - Receptor, trkA KW - Static Electricity KW - Surface Plasmon Resonance KW - X-Rays N1 - Publication Type: Journal Article UR - https://doi.org/10.1002/prot.20366 ER -