TY  - GEN
AU  - Wrigley,Jonathan D J
AU  - Schurov,Irina
AU  - Nunn,Emma J
AU  - Martin,Agnes C L
AU  - Clarke,Earl E
AU  - Ellis,Semantha
AU  - Bonnert,Timothy P
AU  - Shearman,Mark S
AU  - Beher,Dirk
TI  - Functional overexpression of gamma-secretase reveals protease-independent trafficking functions and a critical role of lipids for protease activity
SN  - 0021-9258
PY  - 2005///0513
KW  - Amyloid Precursor Protein Secretases
KW  - Amyloid beta-Protein Precursor
KW  - metabolism
KW  - Aspartic Acid Endopeptidases
KW  - Binding Sites
KW  - Blotting, Western
KW  - Brain
KW  - Catalysis
KW  - Cell Line
KW  - Cell Membrane
KW  - Cell-Free System
KW  - Chromatography
KW  - Culture Media
KW  - Culture Media, Conditioned
KW  - pharmacology
KW  - DNA, Complementary
KW  - Dimerization
KW  - Endopeptidases
KW  - biosynthesis
KW  - Golgi Apparatus
KW  - Humans
KW  - Immunohistochemistry
KW  - Lipid Metabolism
KW  - Membrane Glycoproteins
KW  - Peptide Hydrolases
KW  - Peptides
KW  - chemistry
KW  - Protein Structure, Tertiary
KW  - Time Factors
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1074/jbc.M413086200
ER  -