Chronic ethanol treatment enhances inflammatory mediators and cell death in the brain and in astrocytes. [electronic resource]
- Brain pathology (Zurich, Switzerland) Oct 2004
- 365-71 p. digital
Publication Type: Comparative Study; Journal Article; Research Support, Non-U.S. Gov't
1015-6305
10.1111/j.1750-3639.2004.tb00079.x doi
Animals Animals, Newborn Astrocytes--drug effects Blotting, Western--methods Caspase 3 Caspases--metabolism Cell Death--drug effects Cells, Cultured Central Nervous System Depressants--administration & dosage Cerebral Cortex--cytology Cyclooxygenase 2 DNA Fragmentation--drug effects Electrophoretic Mobility Shift Assay--methods Enzyme-Linked Immunosorbent Assay--methods Ethanol--administration & dosage Female Gene Expression Regulation--drug effects I-kappa B Proteins--metabolism Interleukin-1--genetics Isoenzymes--genetics JNK Mitogen-Activated Protein Kinases--metabolism MAP Kinase Kinase 4 Mitogen-Activated Protein Kinase 3--metabolism Mitogen-Activated Protein Kinase Kinases--metabolism Nitric Oxide Synthase--genetics Nitric Oxide Synthase Type II Prostaglandin-Endoperoxide Synthases--genetics RNA, Messenger--biosynthesis Rats Rats, Wistar Reverse Transcriptase Polymerase Chain Reaction--methods Transcription Factor AP-1--metabolism p38 Mitogen-Activated Protein Kinases--metabolism