Colby, David W <br/><br/>
Potent inhibition of huntingtin aggregation and cytotoxicity by a disulfide bond-free single-domain intracellular antibody.  [electronic resource] 

 -  Proceedings of the National Academy of Sciences of the United States of America  Dec 2004 
 - 17616-21 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, Non-P.H.S. 
<br/><br/><label>ISSN: </label>0027-8424 
<br/><br/><label>Standard No.: </label>10.1073/pnas.0408134101  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Animals<br/>Antibodies--chemistry<br/>Antibody Affinity<br/>Cell Line<br/>Directed Molecular Evolution<br/>Disulfides<br/>Humans<br/>Huntingtin Protein<br/>Huntington Disease--metabolism<br/>Models, Molecular<br/>Mutation--genetics<br/>Nerve Tissue Proteins--chemistry<br/>Nuclear Proteins--chemistry<br/>Protein Binding--drug effects<br/>Protein Denaturation--drug effects<br/>Protein Engineering<br/>Protein Structure, Quaternary--drug effects<br/>Saccharomyces cerevisiae