TY - GEN AU - Tirkkonen,Tuire AU - Laine,Kari TI - Drug interactions with the potential to prevent prodrug activation as a common source of irrational prescribing in hospital inpatients SN - 0009-9236 PY - 2005///0114 KW - Adolescent KW - Adult KW - Aged KW - Aged, 80 and over KW - Analgesics, Opioid KW - pharmacokinetics KW - Antihypertensive Agents KW - Aryl Hydrocarbon Hydroxylases KW - antagonists & inhibitors KW - Biotransformation KW - drug effects KW - Codeine KW - Cytochrome P-450 CYP2C9 KW - Cytochrome P-450 CYP2D6 Inhibitors KW - Databases, Nucleic Acid KW - Drug Interactions KW - Drug Prescriptions KW - economics KW - Enzyme Inhibitors KW - pharmacology KW - Female KW - Humans KW - Losartan KW - Male KW - Medication Errors KW - Medication Systems, Hospital KW - Middle Aged KW - Prodrugs KW - metabolism KW - Sex Factors KW - Tramadol N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1016/j.clpt.2004.08.017 ER -