TY  - GEN
AU  - González-Manchón,Consuelo
AU  - Butta,Nora
AU  - Larrucea,Susana
AU  - Arias-Salgado,Elena G
AU  - Alonso,Sonia
AU  - López,Angela
AU  - Parrilla,Roberto
TI  - A variant thrombasthenic phenotype associated with compound heterozygosity of integrin beta3-subunit: (Met124Val)beta3 alters the subunit dimerization rendering a decreased number of constitutive active alphaIIbbeta3 receptors
SN  - 0340-6245
PY  - 2005///0714
KW  - Alleles
KW  - Amino Acid Sequence
KW  - Animals
KW  - Antigens, Human Platelet
KW  - genetics
KW  - Base Sequence
KW  - Binding Sites
KW  - Blood Platelets
KW  - metabolism
KW  - Blotting, Western
KW  - CHO Cells
KW  - Cell Membrane
KW  - Cricetinae
KW  - DNA Mutational Analysis
KW  - DNA, Complementary
KW  - Dimerization
KW  - Family Health
KW  - Female
KW  - Fibrinogen
KW  - Flow Cytometry
KW  - Genetic Vectors
KW  - Heterozygote
KW  - Humans
KW  - Immunoblotting
KW  - Infant
KW  - Integrin beta3
KW  - chemistry
KW  - Male
KW  - Mice
KW  - Microscopy, Fluorescence
KW  - Molecular Sequence Data
KW  - Mutagenesis
KW  - Mutation
KW  - Phenotype
KW  - Platelet Adhesiveness
KW  - Platelet Glycoprotein GPIIb-IIIa Complex
KW  - Protein Binding
KW  - RNA, Messenger
KW  - Thrombasthenia
KW  - blood
KW  - Time Factors
KW  - Transfection
N1  - Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't
UR  - https://doi.org/10.1160/TH04-06-0380
ER  -