González-Manchón, Consuelo <br/><br/>
A variant thrombasthenic phenotype associated with compound heterozygosity of integrin beta3-subunit: (Met124Val)beta3 alters the subunit dimerization rendering a decreased number of constitutive active alphaIIbbeta3 receptors.  [electronic resource] 

 -  Thrombosis and haemostasis  Dec 2004 
 - 1377-86 p.  digital 
<br/><br/> Publication Type: Case Reports; Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0340-6245 
<br/><br/><label>Standard No.: </label>10.1160/TH04-06-0380  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alleles<br/>Amino Acid Sequence<br/>Animals<br/>Antigens, Human Platelet--genetics<br/>Base Sequence<br/>Binding Sites<br/>Blood Platelets--metabolism<br/>Blotting, Western<br/>CHO Cells<br/>Cell Membrane--metabolism<br/>Cricetinae<br/>DNA Mutational Analysis<br/>DNA, Complementary--metabolism<br/>Dimerization<br/>Family Health<br/>Female<br/>Fibrinogen--metabolism<br/>Flow Cytometry<br/>Genetic Vectors<br/>Heterozygote<br/>Humans<br/>Immunoblotting<br/>Infant<br/>Integrin beta3--chemistry<br/>Male<br/>Mice<br/>Microscopy, Fluorescence<br/>Molecular Sequence Data<br/>Mutagenesis<br/>Mutation<br/>Phenotype<br/>Platelet Adhesiveness<br/>Platelet Glycoprotein GPIIb-IIIa Complex--chemistry<br/>Protein Binding<br/>RNA, Messenger--metabolism<br/>Thrombasthenia--blood<br/>Time Factors<br/>Transfection