TY - GEN AU - Becker,Richard C AU - Alexander,John AU - Dyke,Christopher K AU - Harrington,Robert A TI - Development of DX-9065a, a novel direct factor Xa antagonist, in cardiovascular disease SN - 0340-6245 PY - 2005///0714 KW - Animals KW - Anticoagulants KW - pharmacology KW - Area Under Curve KW - Blood Coagulation KW - Cardiovascular Diseases KW - drug therapy KW - Clinical Trials as Topic KW - Coronary Artery Disease KW - Disease Models, Animal KW - Dose-Response Relationship, Drug KW - Factor Xa KW - chemistry KW - Factor Xa Inhibitors KW - Humans KW - International Normalized Ratio KW - Mice KW - Models, Biological KW - Models, Chemical KW - Naphthalenes KW - Pilot Projects KW - Platelet Aggregation Inhibitors KW - Propionates KW - Rats KW - Thrombin KW - metabolism KW - Thromboplastin KW - Thrombosis KW - Time Factors N1 - Publication Type: Journal Article; Review UR - https://doi.org/10.1160/TH04-05-0289 ER -