TY  - GEN
AU  - Guengerich,F Peter
TI  - Principles of covalent binding of reactive metabolites and examples of activation of bis-electrophiles by conjugation
SN  - 0003-9861
PY  - 2005///0127
KW  - Aflatoxin B1
KW  - chemistry
KW  - Animals
KW  - Biotransformation
KW  - Butadienes
KW  - Cross-Linking Reagents
KW  - DNA
KW  - DNA Adducts
KW  - DNA Damage
KW  - DNA Repair
KW  - Dose-Response Relationship, Drug
KW  - Enzyme Activation
KW  - Escherichia coli
KW  - drug effects
KW  - Ethylene Dibromide
KW  - Forecasting
KW  - Genes, Bacterial
KW  - Glutathione
KW  - metabolism
KW  - Half-Life
KW  - Humans
KW  - Hydrolysis
KW  - Kinetics
KW  - Lysine
KW  - Models, Chemical
KW  - Molecular Structure
KW  - Mutagenicity Tests
KW  - Mutagens
KW  - Mutation
KW  - O(6)-Methylguanine-DNA Methyltransferase
KW  - Oxidation-Reduction
KW  - Salmonella typhimurium
KW  - Signal Transduction
KW  - Tetrachloroethylene
KW  - Trichloroethylene
N1  - Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review
UR  - https://doi.org/10.1016/j.abb.2004.07.035
ER  -