Guengerich, F Peter <br/><br/>
Principles of covalent binding of reactive metabolites and examples of activation of bis-electrophiles by conjugation.  [electronic resource] 

 -  Archives of biochemistry and biophysics  Jan 2005 
 - 369-78 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, U.S. Gov't, P.H.S.; Review 
<br/><br/><label>ISSN: </label>0003-9861 
<br/><br/><label>Standard No.: </label>10.1016/j.abb.2004.07.035  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Aflatoxin B1--chemistry<br/>Animals<br/>Biotransformation<br/>Butadienes--chemistry<br/>Cross-Linking Reagents--chemistry<br/>DNA<br/>DNA Adducts--chemistry<br/>DNA Damage<br/>DNA Repair<br/>Dose-Response Relationship, Drug<br/>Enzyme Activation<br/>Escherichia coli--drug effects<br/>Ethylene Dibromide--chemistry<br/>Forecasting<br/>Genes, Bacterial<br/>Glutathione--metabolism<br/>Half-Life<br/>Humans<br/>Hydrolysis<br/>Kinetics<br/>Lysine--metabolism<br/>Models, Chemical<br/>Molecular Structure<br/>Mutagenicity Tests<br/>Mutagens--chemistry<br/>Mutation<br/>O(6)-Methylguanine-DNA Methyltransferase--metabolism<br/>Oxidation-Reduction<br/>Salmonella typhimurium--drug effects<br/>Signal Transduction<br/>Tetrachloroethylene--chemistry<br/>Trichloroethylene--chemistry