TY  - GEN
AU  - Denley,Adam
AU  - Wang,Chunxiao C
AU  - McNeil,Kerrie A
AU  - Walenkamp,Marie J E
AU  - van Duyvenvoorde,Hermine
AU  - Wit,Jan M
AU  - Wallace,John C
AU  - Norton,Raymond S
AU  - Karperien,Marcel
AU  - Forbes,Briony E
TI  - Structural and functional characteristics of the Val44Met insulin-like growth factor I missense mutation: correlation with effects on growth and development
SN  - 0888-8809
PY  - 2005///0628
KW  - Binding Sites
KW  - Binding, Competitive
KW  - Biological Assay
KW  - Blotting, Western
KW  - Cell Proliferation
KW  - DNA
KW  - metabolism
KW  - DNA Mutational Analysis
KW  - Dose-Response Relationship, Drug
KW  - Fibroblasts
KW  - Humans
KW  - Immunoprecipitation
KW  - Inhibitory Concentration 50
KW  - Insulin
KW  - Insulin-Like Growth Factor I
KW  - genetics
KW  - Ligands
KW  - Magnetic Resonance Spectroscopy
KW  - Methionine
KW  - chemistry
KW  - Mitogen-Activated Protein Kinase 1
KW  - Mitogen-Activated Protein Kinase 3
KW  - Models, Molecular
KW  - Mutation
KW  - Mutation, Missense
KW  - Phenotype
KW  - Phosphorylation
KW  - Plasmids
KW  - Protein Binding
KW  - Protein Isoforms
KW  - Protein Serine-Threonine Kinases
KW  - Proto-Oncogene Proteins
KW  - Proto-Oncogene Proteins c-akt
KW  - Receptor, IGF Type 1
KW  - Recombinant Proteins
KW  - Signal Transduction
KW  - Surface Plasmon Resonance
KW  - Thymidine
KW  - Time Factors
KW  - Valine
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1210/me.2004-0409
ER  -