TY - GEN AU - Chen,Hsin-Yi AU - Shen,Che-Hung AU - Tsai,Yuh-Tyng AU - Lin,Feng-Chi AU - Huang,Yuan-Ping AU - Chen,Ruey-Hwa TI - Brk activates rac1 and promotes cell migration and invasion by phosphorylating paxillin SN - 0270-7306 PY - 2004///1230 KW - Animals KW - COS Cells KW - Catalytic Domain KW - Cell Adhesion Molecules KW - metabolism KW - Cell Line KW - Cell Line, Tumor KW - Cell Movement KW - Chemotaxis KW - drug effects KW - Chlorocebus aethiops KW - Cytoskeletal Proteins KW - Enzyme Activation KW - Epidermal Growth Factor KW - Glutathione Transferase KW - Green Fluorescent Proteins KW - HeLa Cells KW - Humans KW - Kinetics KW - Microscopy, Fluorescence KW - Models, Biological KW - Neoplasm Proteins KW - Paxillin KW - Phosphoproteins KW - Phosphorylation KW - Precipitin Tests KW - Protein Structure, Tertiary KW - Protein-Tyrosine Kinases KW - analysis KW - Proto-Oncogene Proteins KW - Proto-Oncogene Proteins c-crk KW - RNA, Small Interfering KW - Recombinant Fusion Proteins KW - Signal Transduction KW - Substrate Specificity KW - rac1 GTP-Binding Protein N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1128/MCB.24.24.10558-10572.2004 ER -