TY  - GEN
AU  - Macdonald,Simon J F
AU  - Watson,Keith G
AU  - Cameron,Rachel
AU  - Chalmers,David K
AU  - Demaine,Derek A
AU  - Fenton,Rob J
AU  - Gower,David
AU  - Hamblin,J Nicole
AU  - Hamilton,Stephanie
AU  - Hart,Graham J
AU  - Inglis,Graham G A
AU  - Jin,Betty
AU  - Jones,Haydn T
AU  - McConnell,Darryl B
AU  - Mason,Andy M
AU  - Nguyen,Van
AU  - Owens,Ian J
AU  - Parry,Nigel
AU  - Reece,Phillip A
AU  - Shanahan,Stephen E
AU  - Smith,Donna
AU  - Wu,Wen-Yang
AU  - Tucker,Simon P
TI  - Potent and long-acting dimeric inhibitors of influenza virus neuraminidase are effective at a once-weekly dosing regimen
SN  - 0066-4804
PY  - 2005///0118
KW  - Animals
KW  - Antiviral Agents
KW  - administration & dosage
KW  - Cell Line
KW  - Chromatography, Gel
KW  - Cytopathogenic Effect, Viral
KW  - drug effects
KW  - Dogs
KW  - Enzyme Inhibitors
KW  - Guanidines
KW  - Indicators and Reagents
KW  - Kinetics
KW  - Lung
KW  - metabolism
KW  - Male
KW  - Mice
KW  - Microscopy, Electron
KW  - Neuraminidase
KW  - antagonists & inhibitors
KW  - Orthomyxoviridae
KW  - Orthomyxoviridae Infections
KW  - prevention & control
KW  - Pyrans
KW  - Rats
KW  - Rats, Sprague-Dawley
KW  - Sialic Acids
KW  - chemistry
KW  - Structure-Activity Relationship
KW  - Viral Plaque Assay
KW  - Virus Replication
KW  - Zanamivir
N1  - Publication Type: Journal Article
UR  - https://doi.org/10.1128/AAC.48.12.4542-4549.2004
ER  -