TY - GEN AU - Koldamova,Radosveta P AU - Lefterov,Iliya M AU - Staufenbiel,Matthias AU - Wolfe,Darren AU - Huang,Shaohua AU - Glorioso,Joseph C AU - Walter,Michael AU - Roth,Michael G AU - Lazo,John S TI - The liver X receptor ligand T0901317 decreases amyloid beta production in vitro and in a mouse model of Alzheimer's disease SN - 0021-9258 PY - 2005///0405 KW - Alzheimer Disease KW - metabolism KW - Amyloid beta-Protein Precursor KW - genetics KW - Animals KW - Anticholesteremic Agents KW - pharmacology KW - Apolipoprotein A-I KW - chemistry KW - Blotting, Western KW - Brain KW - Cloning, Molecular KW - DNA, Complementary KW - DNA-Binding Proteins KW - Disease Models, Animal KW - Enzyme-Linked Immunosorbent Assay KW - Fibroblasts KW - Humans KW - Hydrocarbons, Fluorinated KW - Immunoprecipitation KW - Ligands KW - Liver X Receptors KW - Mice KW - Mice, Inbred C57BL KW - Mice, Transgenic KW - Neurons KW - Orphan Nuclear Receptors KW - Protein Binding KW - Receptors, Cytoplasmic and Nuclear KW - Simplexvirus KW - Sulfonamides KW - Time Factors KW - Transcription, Genetic KW - Transfection KW - Up-Regulation N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't; Research Support, U.S. Gov't, P.H.S UR - https://doi.org/10.1074/jbc.M411420200 ER -