A major histocompatibility complex-peptide-restricted antibody and t cell receptor molecules recognize their target by distinct binding modes: crystal structure of human leukocyte antigen (HLA)-A1-MAGE-A1 in complex with FAB-HYB3. [electronic resource]
- The Journal of biological chemistry Jan 2005
- 2972-80 p. digital
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
0021-9258
10.1074/jbc.M411323200 doi
Amino Acid Sequence Antigens, Neoplasm Crystallography, X-Ray HLA-A1 Antigen--chemistry Humans Hydrogen Bonding Immunoglobulin Fab Fragments--chemistry Ligands Major Histocompatibility Complex Melanoma-Specific Antigens Models, Molecular Molecular Sequence Data Neoplasm Proteins--chemistry Peptides--chemistry Protein Binding Protein Conformation Protein Structure, Secondary Protein Structure, Tertiary Receptors, Antigen, T-Cell--metabolism Water--chemistry