TY - GEN AU - Chambers,Mark S AU - Atack,John R AU - Carling,Robert W AU - Collinson,Neil AU - Cook,Susan M AU - Dawson,Gerard R AU - Ferris,Pushpindar AU - Hobbs,Sarah C AU - O'connor,Desmond AU - Marshall,George AU - Rycroft,W AU - Macleod,Angus M TI - An orally bioavailable, functionally selective inverse agonist at the benzodiazepine site of GABAA alpha5 receptors with cognition enhancing properties SN - 0022-2623 PY - 2005///0103 KW - Administration, Oral KW - Animals KW - Binding Sites KW - Biological Availability KW - Cognition KW - drug effects KW - Dogs KW - GABA-A Receptor Agonists KW - Isoxazoles KW - adverse effects KW - Maze Learning KW - Mice KW - Nootropic Agents KW - Patch-Clamp Techniques KW - Protein Subunits KW - Radioligand Assay KW - Rats KW - Receptors, GABA-A KW - metabolism KW - Triazines N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm040863t ER -