TY - GEN AU - Lindsley,Craig W AU - Wisnoski,David D AU - Leister,William H AU - O'brien,Julie A AU - Lemaire,Wei AU - Williams,David L AU - Burno,Maryann AU - Sur,Cyrille AU - Kinney,Gene G AU - Pettibone,Doug J AU - Tiller,Philip R AU - Smith,Sheri AU - Duggan,Mark E AU - Hartman,George D AU - Conn,P Jeffrey AU - Huff,Joel R TI - Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo SN - 0022-2623 PY - 2005///0103 KW - Allosteric Regulation KW - Animals KW - Antipsychotic Agents KW - chemical synthesis KW - Benzamides KW - Brain KW - metabolism KW - CHO Cells KW - Cricetinae KW - Cricetulus KW - Glutamic Acid KW - pharmacology KW - Humans KW - In Vitro Techniques KW - Pyrazoles KW - Rats KW - Receptor, Metabotropic Glutamate 5 KW - Receptors, Metabotropic Glutamate KW - drug effects KW - Reflex, Startle KW - Structure-Activity Relationship N1 - Publication Type: Journal Article UR - https://doi.org/10.1021/jm049400d ER -