Lindsley, Craig W <br/><br/>
Discovery of positive allosteric modulators for the metabotropic glutamate receptor subtype 5 from a series of N-(1,3-diphenyl-1H- pyrazol-5-yl)benzamides that potentiate receptor function in vivo.  [electronic resource] 

 -  Journal of medicinal chemistry  Nov 2004 
 - 5825-8 p.  digital 
<br/><br/> Publication Type: Journal Article 
<br/><br/><label>ISSN: </label>0022-2623 
<br/><br/><label>Standard No.: </label>10.1021/jm049400d  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Allosteric Regulation<br/>Animals<br/>Antipsychotic Agents--chemical synthesis<br/>Benzamides--chemical synthesis<br/>Brain--metabolism<br/>CHO Cells<br/>Cricetinae<br/>Cricetulus<br/>Glutamic Acid--pharmacology<br/>Humans<br/>In Vitro Techniques<br/>Pyrazoles--chemical synthesis<br/>Rats<br/>Receptor, Metabotropic Glutamate 5<br/>Receptors, Metabotropic Glutamate--drug effects<br/>Reflex, Startle--drug effects<br/>Structure-Activity Relationship