TY - GEN AU - Frerichs-Deeken,Ursula AU - Ranguelova,Kalina AU - Kappl,Reinhard AU - Hüttermann,Jürgen AU - Fetzner,Susanne TI - Dioxygenases without requirement for cofactors and their chemical model reaction: compulsory order ternary complex mechanism of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase involving general base catalysis by histidine 251 and single-electron oxidation of the substrate dianion SN - 0006-2960 PY - 2005///0111 KW - Alanine KW - genetics KW - Anaerobiosis KW - Arthrobacter KW - enzymology KW - Bacterial Proteins KW - antagonists & inhibitors KW - Binding Sites KW - Catalysis KW - Dioxygenases KW - Electron Spin Resonance Spectroscopy KW - Electrons KW - Enzyme Activation KW - Escherichia coli Proteins KW - chemistry KW - Histidine KW - Hydrogen Peroxide KW - Hydrogen-Ion Concentration KW - Kinetics KW - Models, Chemical KW - Mutagenesis, Site-Directed KW - Oxidation-Reduction KW - Oxygen KW - Quinaldines KW - Spectrophotometry, Ultraviolet KW - Substrate Specificity N1 - Publication Type: Journal Article; Research Support, Non-U.S. Gov't UR - https://doi.org/10.1021/bi048735u ER -