Frerichs-Deeken, Ursula <br/><br/>
Dioxygenases without requirement for cofactors and their chemical model reaction: compulsory order ternary complex mechanism of 1H-3-hydroxy-4-oxoquinaldine 2,4-dioxygenase involving general base catalysis by histidine 251 and single-electron oxidation of the substrate dianion.  [electronic resource] 

 -  Biochemistry  Nov 2004 
 - 14485-99 p.  digital 
<br/><br/> Publication Type: Journal Article; Research Support, Non-U.S. Gov't 
<br/><br/><label>ISSN: </label>0006-2960 
<br/><br/><label>Standard No.: </label>10.1021/bi048735u  doi 
<br/><br/><label>Subjects--Topical Terms: </label><br/>Alanine--genetics<br/>Anaerobiosis--genetics<br/>Arthrobacter--enzymology<br/>Bacterial Proteins--antagonists & inhibitors<br/>Binding Sites<br/>Catalysis<br/>Dioxygenases--antagonists & inhibitors<br/>Electron Spin Resonance Spectroscopy<br/>Electrons<br/>Enzyme Activation--genetics<br/>Escherichia coli Proteins--chemistry<br/>Histidine--chemistry<br/>Hydrogen Peroxide--chemistry<br/>Hydrogen-Ion Concentration<br/>Kinetics<br/>Models, Chemical<br/>Mutagenesis, Site-Directed<br/>Oxidation-Reduction<br/>Oxygen--chemistry<br/>Quinaldines--chemistry<br/>Spectrophotometry, Ultraviolet<br/>Substrate Specificity